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澳門新葡官網進入 學校首頁 | 學院首頁 
         
康貴峰

姓名:康貴峰

性別:男

職稱:講師

 

招生院所:澳門新葡官網進入

招生類型:

招生專業:藥物化學

研究方向名稱:藥物化學,有機化學

電子信箱:guifengkang@qq.com

個人簡介

2016年進入多肽及小分子藥物北京市重點實驗室,任藥物化學系講師。講授課程包括藥物化學、有機化學、藥物的波譜解析實驗、專業藥學實驗等。

研究方向為雜環小分子的設計、合成、活性評價及作用機制研究。

 

教育經歷

2005/8 - 2008/7,北京大學澳門新葡官網進入,博士,導師:彭師奇、趙明。

2002/9 - 2005/7,中國科學院山西煤化所,碩士,導師:王建國。

1998/9 - 2002/7,西北大學化學系,學士。

 

工作經歷

2016/1 - 至今,澳門新葡官網進入化學生物學院澳門新葡官網進入,教師

2014/9 - 2015/12,美國弗吉尼亞聯邦大學藥物化學系,博士后

2012/4 - 2013/11,北京四環制藥,項目經理

2009/12 - 2014/1,浙江大學、浙江醫藥股份有限公司新昌制藥廠聯合培養,博士后

2009/12 - 2012/3,浙江醫藥股份有限公司新昌制藥廠,職工

2008/9 - 2009/10,康龍化成(北京)新藥技術有限公司,高級研究員

 

重要學術論文

1. Guifeng Kang, Yuji Wang, Jiawang Liu, Jianhui Wu, Ming Zhao, Guochun Li, Ning Li, Li Peng, Xiaoyi Zhang, Li Li, Nathan Mair, Shiqi Peng, Development of three-component conjugates : to get nano-globes with pouous surfaces, high in vivo anti-osteoporosis activity and minimal side effects, J.Mater. Chem.,09/ 2012, 22(40), 21740-21748.

2. Guifeng Kang, Ming Zhao, Xiaoyi Zhang, Li Peng, Chunbo Li, Wei Mao, Weidong Ye, Shiqi Peng “A class of novel conjugates of substituted purine and Gly-AA-OBzl: Synthesis and evaluation of orally analgesic activity”, Bioorg. Med. Chem. Lett.,10/2010, 20(20), 6157-6160.

3. Yuji Wang, Guifeng Kang, Jiawang Liu, Ming Zhao, Jianhui Wu, Xiaoyi Zhang, Ye Li, Xiaobo Zhong, Yifan Yang, Shiqi Peng, Novel potassium N-[(2S, 3R, 4R, 5R)-2,3,4,5,6-pentahy -droxylhex-1-yl]-L-amino acid dichloroplatinates(II) with high anti-tumor activity and low side reaction, Metallomics, 04/2012, 4(5), 441-447.

4. Jinghua Zhao, Guifeng Kang, Wei Wang, Ming Zhao, Xiaoyi Zhang, Chunbo Lu, Wei Mao, Heng Wei Chang, Weidong Ye, Shiqi Peng, N-[2-Chloro-9H-purin-6-yl]-N- cyclopropylgly- cylamino acids and derivatives: Synthesis, evaluation as a class of novel analgesics, and 3D QSAR analysis, Bioorg. Med. Chem., 08/2009, 17 (17), 6305-6310.

5. Yuji Wang, Guifeng Kang, Ming Zhao, Jianhui Wu, Xiaoyi Zhang, Yifan Yang, Jiawang Liu, Shiqi Peng, A new platinum-complex show easy preparation, promising anti-tumor activity, and better efficacy and distribution properties than oxaliplatin, Mol. BioSyst., 12/2011, 7(12), 3245-3252.

6. Ning Li, Guifeng Kang, Lin Gui, Ming Zhao, Wenjing Wang, Jianwei Zhang, Yan-Feng Yue, Shiqi Peng, Novel Cu(II)-RGD-octapeptides: Synthesis, coordination mode, in vitro anti-platelet aggregation/in vivo anti-thrombotic evaluation and correlation of sequence with nano-structure., Nanomed- Nanotechnol., 01/2011, 7(4), 403-409.

7. Yuji Wang, Jianhui Wu, Guifeng Kang, Ming Zhao, Lin Gui,Ning Li, Li Peng, Xiaoyi Zhang, Li Li, Shiqi Peng, Novel nano-materials RGD-tetrapeptide-modified 17β-amino-11α- hydroxyandrost-1,4-diene-3-one: synthesis, self-assembly based nano-images and in vivo anti-osteoporosis evaluation, J.Mater. Chem.,02/2012, 22(11), 4652-4659.

8. Yuji Wang, Jianhui Wu, Guifeng Kang, Ming Zhao, Lin Gui,Ning Li, Li Peng, Xiaoyi Zhang, Li Li, Shiqi Peng, Novel nano-materials RGD-tetrapeptide-modified 17β-amino-11α- hydroxyandrost-1,4-diene-3-one: synthesis, self-assembly based nano-images and in vivo anti-osteoporosis evaluation, J.Mater. Chem.,02/2012, 22(11), 4652-4659.

9. Jingcheng Tang, Ming Zhao, Yuji Wang, Guifeng Kang, Jianhui Wu, Meiqing Zheng, Shiqi Peng, One single HPLC-PDA/(-)ESI-MS/MS analysis to simultaneously determine 30 components of the aqueous extract of Rabdosia rubescens,  J. Chromatogr. B., 09/2011, 879 (26) 2783-2793.

10. Jianhui Wu, Lei Wei, Ming Zhao, Yuji Wang, Guifeng Kang, Shiqi Peng, N-[2(3-Carboxyl-9-benzyl-carboline-1-yl)ethyl-1- yl]-amino acids: correlation of spectral property with in vivo anti-tumor activity, Med. Chem. Res., 04/2012, 21(1), 116-123.

11. Wenjing Wang, Ming Zhao, Yuji Wang, Jiawang Liu, Jianhui Wu, Guifeng Kang and Shiqi Peng, {2-[1-(3-Methoxycarbonylmethyl -1H-indol-2-yl)-1-methyl-ethyl]-1H-indol-3-yl}- acetic acid methyl ester (MIAM): Its anti-cancer efficacy and intercalation mechanism identified via multi-model systems, Mol. BioSyst., 03/2011, 7(3), 766-772.

 

主編或副主編的著作/譯著

 

重要獎項

 



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